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Updated: Jul 13, 2026

Closure of a Patent Foramen Ovale (PFO): An Intervention Sequence
Published on: December 23, 2022
Early Amplatzer occluder closure of a postinfarct ventricular septal defect as a bridge to surgical procedure
Victor S Costache1, Olivier Chavanon, Hélène Bouvaist
1Department of Cardiac Surgery, Grenoble University Hospital, Grenoble, France.
Insights
Postinfarction ventricular septal defects are challenging. Percutaneous closure using an Amplatzer occluder (AO) improved a patient's condition, enabling delayed surgical repair with excellent outcomes.
Area of Science:
- Cardiology
- Cardiac Surgery
- Interventional Cardiology
Background:
- Postinfarction ventricular septal defects (VSD) pose significant management challenges due to high morbidity and mortality.
- Early diagnosis and intervention are crucial for improving patient outcomes in these critical cases.
Observation:
- A 79-year-old patient presented with an apical VSD nine days after an anterior myocardial infarction.
- The patient experienced cardiogenic shock and acute pulmonary edema, necessitating urgent intervention.
Findings:
- Percutaneous closure of the VSD was performed using an Amplatzer occluder (AO).
- Despite incomplete initial closure, the AO device significantly improved the patient's clinical status.
- This allowed for a successful surgical VSD repair ten days post-intervention.
Implications:
- Percutaneous VSD closure can serve as a valuable bridge to surgical repair, stabilizing patients in cardiogenic shock.
- This approach may reduce the risks associated with immediate surgical intervention in high-risk patients.
- The findings highlight the potential of interventional techniques in managing complex postinfarction complications.
Abstract:
The management of postinfarction ventricular septal defects represents a challenge to both cardiologists and surgeons due to the high morbidity and mortality rate. We report the case of a 79-year-old patient who developed an apical rupture of the ventricular septum, nine days after an anterior myocardial infarction. As the patient was in cardiogenic shock and developed acute pulmonary edema we chose to perform a percutaneous closure of the septal defect using an Amplatzer occluder (AO). Despite the incomplete closure, the placement of the device greatly improved the patient's clinical condition allowing the delay of the surgical procedure, which could be performed ten days later with an excellent result.
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