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Updated: Jul 13, 2026

Normothermic Negative Pressure Ventilation Ex Situ Lung Perfusion: Evaluation of Lung Function and Metabolism
Published on: February 14, 2022
The value of a preoperative ventilation-perfusion scan in patient selection for pneumonectomy
Anand Sachithanandan1, Shilajit Ghosh
1Division of Thoracic Surgery, Birmingham Heartlands Hospital, Bordersley Green East, Birmingham B9 5SS, UK. anandsachithanandan@yahoo.com
Abstract:
Guidelines regarding operability of patients with lung cancer are well established. The measured and predicted pulmonary function provides a practical guide to the safety of lobectomy or pneumonectomy. We describe a patient who had an unexplained precipitous fall in preoperative FEV(1) that would have precluded a required pneumonectomy but for an urgent ventilation-perfusion (V/Q) scan. This case highlights the fact that clinical acumen rather than a strict adherence to established guidelines is vital in the assessment of lung cancer patients awaiting potentially curative surgery.
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