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Which place for Port Access surgery in coronary artery bypass grafting? A mid-term follow up study
Fadi Farhat1, Mathieu Vergnat, Pascale Blanc
1Department of Cardiovascular Surgery (Pr Jegaden), Hôpital Pradel, Université Claude Bernard, INSERM E0226, 28, avenue du doyen Lepine, 69677 Bron Cedex, France. fadi.farhat@chu-lyon.fr
Insights
Port Access Coronary Artery Bypass Grafting (CABG) is a safe surgical option for patients with one or two-vessel disease. This minimally invasive technique demonstrates stable mid-term results, including reduced angina symptoms and patent grafts.
Area of Science:
- Cardiovascular Surgery
- Minimally Invasive Cardiac Surgery
- Vascular Surgery
Background:
- Coronary artery bypass grafting (CABG) is a standard treatment for coronary artery disease.
- Minimally invasive approaches aim to reduce surgical trauma and improve patient recovery.
- Port Access CABG utilizes cardiopulmonary bypass (CPB) via peripheral cannulation and smaller incisions.
Purpose of the Study:
- To evaluate the safety and efficacy of Port Access CABG using the Heartport endoCPB system.
- To assess mid-term clinical outcomes and graft patency in patients with one or two-vessel disease.
Main Methods:
- A prospective study of 68 patients with one or two-vessel disease undergoing Port Access CABG between May 1997 and November 2002.
- Utilized the Heartport endoCPB system with various graft conduits, including internal thoracic arteries and radial artery.
- Collected data on operative times, CPB duration, postoperative recovery, clinical outcomes, and graft patency at mid-term follow-up.
Main Results:
- Mean operative time was 3.8 hours, with cross-clamping and CPB times of 42 and 64 minutes, respectively.
- Postoperative outcomes included short ventilation times (11 hours), ICU stay of 1.9 days, and low blood loss (398 ml).
- Significant reduction in Canadian Cardiovascular Society (CCS) score (3.1 to 1.1, P<0.0001) and patent grafts in all cases at 4.1 years follow-up.
Conclusions:
- Port Access CABG is a safe and effective surgical option for selected patients with one or two-vessel coronary artery disease.
- The technique provides stable mid-term results, characterized by symptom improvement and durable graft patency.
- Minimally invasive CABG can be considered a viable alternative to conventional sternotomy for appropriate patient populations.
Abstract:
Between May 1997 and November 2002, 68 patients with one or two-vessel disease (55+/-9 years) underwent Port Access CABG using the Heartport endoCPB. The LITA was used in 63 cases, the RITA in 14, a radial artery in 2 and a vein graft in 3. Mean distal anastomoses was 1.3+/-0.5. Cross clamping, CPB, and operative times were 42+/-20 min, 64+/-27 min, and 3.8+/-1.5 h. Postoperative ventilation was 11+/-17 h, and ICU stay was 1.9+/-2.6 days. At day-1, troponin level was 2.3+/-2.9 UI and blood loss was 398+/-240 ml. Two patients needed long intubation and two had pleural re-drainage. One patient had a stroke, one had a myocardial infarction, and one underwent revision for bleeding. Hospital stay was 7+/-3 days. 65% were discharged to home. Follow up was completed in all cases (4.1+/-1.8 years). CCS score was significantly reduced (from 3.1+/-0.3 to 1.1+/-0.3, P<0.0001). Two patients had PTCA and stenting of non-grafted arteries. Five other patients had recurrent angina. Angiograms showed patent grafts in all cases. Two patients died after 19 months and 5 years from non cardiac reasons. In conclusion, Port Access CABG remains a safe technique with stable results at mid-term follow up.
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