Related Experiment Video
Updated: Jul 13, 2026

A Hydrogel Construct and Fibrin-based Glue Approach to Deliver Therapeutics in a Murine Myocardial Infarction Model.
Published on: June 14, 2015
Chinese-hat patch glue repair of incomplete apical ventricular rupture
Matthew Panagiotou1, Efstratios N Koletsis, Konstantinos Markakis
1Department of Cardiac Surgery, Athens Medical Center, Athens, Greece.
Abstract:
Left ventricular free wall rupture is a dramatic complication of myocardial infarction. Sub-acute rupture may be compatible with life for several days or even longer. We present a simple and effective technique of construction of a conical apical patch, Chinese-hat, which was applied successfully to the infracted left ventricular (LV) apex with surgical glue, without using cardiopulmonary bypass. The application of this technique permitted the consequent off-pump double coronary artery bypass of a patient, who was at high risk of complications due to extracorporeal circulation.

