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Related Concept Videos

Herniated Intervertebral Disc l: Introduction01:29

Herniated Intervertebral Disc l: Introduction

Intervertebral disc herniation refers to the displacement of the nucleus pulposus (the gel-like inner core of the disc) through a tear or weakened area in the annulus fibrosus (the outer fibrous ring). The displaced disc material extends beyond the normal boundaries of the disc space and may compress or irritate nearby spinal nerve roots or, less commonly, the spinal cord.Etiology and Risk FactorsHerniation commonly results from degeneration, in which aging reduces disc hydration and...
Degenerative Disc Disease I: Introduction01:27

Degenerative Disc Disease I: Introduction

Degenerative disc disease is a chronic condition in which intervertebral discs gradually lose structure and function. It is not infectious or autoimmune; rather, it results from age-related biochemical and mechanical changes, influenced by genetic, metabolic, and environmental factors.Structure and Function of DiscsThe spine contains 23 intervertebral discs that absorb load, distribute forces, maintain spacing, and allow flexibility. Each disc consists of a nucleus pulposus, a gel-like core...
Degenerative Disc Disease ll: Pathophysiology01:23

Degenerative Disc Disease ll: Pathophysiology

The symptoms of degenerative disc disease arise from a combination of mechanical compression, vascular compromise, and biochemical inflammation, which together disrupt nerve function and produce pain.Mechanical CompressionDisc degeneration reduces height and elasticity, predisposing to herniation of the nucleus pulposus, a major cause of radicular pain. Herniations may be protrusion (bulging with intact annulus), extrusion (nucleus extends beyond disc but remains connected), or sequestration...
Structural Joints: Cartilaginous Joints01:17

Structural Joints: Cartilaginous Joints

As the name indicates, at a cartilaginous joint, the adjacent bones are united by cartilage, a tough but flexible type of connective tissue. Unlike synovial joints, these types of joints lack a joint cavity and involve bones joined together by either hyaline cartilage or fibrocartilage.
There are two types of cartilaginous joints:
Synchondrosis
A synchondrosis ("joined by cartilage") is a cartilaginous joint where bones are connected by hyaline cartilage. Synchondrosis may be temporary or...

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Related Experiment Video

Updated: Jul 13, 2026

A Mouse Model of Lumbar Spine Instability
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[Intervertebral diskitis in children].

Iu K Abaev

    Vestnik Khirurgii Imeni I. I. Grekova
    |August 4, 2007
    PubMed
    Summary

    This study analyzed intervertebral discitis in 16 children, finding conservative treatments like antibiotics and immobilization effective. Magnetic Resonance Imaging (MRT) is highly informative for diagnosing this spinal condition.

    Area of Science:

    • Pediatric Orthopedics
    • Infectious Diseases
    • Radiology

    Background:

    • Intervertebral discitis is a spinal infection affecting children.
    • Understanding its clinical presentation across different spinal regions is crucial for diagnosis and management.
    • The role of advanced imaging in pediatric spinal infections requires clear definition.

    Purpose of the Study:

    • To analyze the treatment of intervertebral discitis in a pediatric cohort.
    • To describe the clinical manifestations of discitis based on spinal localization.
    • To evaluate the diagnostic utility of Magnetic Resonance Imaging (MRT).

    Main Methods:

    • Retrospective analysis of 16 pediatric patients (1.5-15 years) diagnosed with intervertebral discitis.
    • Detailed review of clinical presentations, spinal segment involvement (cervical, thoracic, lumbar, lumbosacral).

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  • Assessment of treatment outcomes focusing on conservative modalities.

    • Main Results:

    • Discitis occurred most frequently in the cervical spine (9/16 children).
    • Specific clinical syndromes were associated with discitis localization.
    • Magnetic Resonance Imaging (MRT) demonstrated high diagnostic value.

    Conclusions:

    • Conservative treatment, including antibiotics and immobilization, is the primary approach for pediatric intervertebral discitis.
    • Accurate diagnosis and management depend on recognizing location-specific clinical features.
    • MRT is an essential tool for the effective evaluation of pediatric discitis.