Related Experiment Video
Updated: Jul 13, 2026
19:57
An Affordable HIV-1 Drug Resistance Monitoring Method for Resource Limited Settings
Published on: March 30, 2014
[Molecular epidemiologic characteristics of HIV-1 variants isolated in the Lipetsk region]
Zhurnal Mikrobiologii, Epidemiologii I Immunobiologii
|August 4, 2007
Abstract:
Molecular epidemiologic study of HIV-1 variants isolated in the Lipetsk region during 1994 - 2006 period was performed. It has been shown that 3 env-subtypes (A, B, and C) and 3 gag-subtypes (A, B, and C) are widespread in the region. The virus was transmitted both sexually and by injecting drug users. Phylogenetic analysis of gag and env genes nucleotide sequences was performed, which revealed that 4 variants of HIV-1 with genotypes gagA/envA, gagB/envB, gagC/envC, and recombinant gagA/envB are circulating in the region.
More Related Videos
Related Concept Videos
00:36Viral Mutations
A mutation is a change in the sequence of bases of DNA or RNA in a genome. Some mutations occur during replication of the genome due to errors made by the polymerase enzymes that replicate DNA or RNA. Unlike DNA polymerase, RNA polymerase is prone to errors because it is not capable of “proofreading” its work. Viruses with RNA-based genomes, like HIV, therefore accrue mutations faster than viruses with DNA-based genomes. Because mutation and recombination provide the raw material for adaptive...
01:28Herpes
Herpes simplex type 1 (HSV‑1) is a widespread pathogen responsible for orolabial lesions. It is an enveloped, double-stranded DNA (dsDNA) virus belonging to the family Herpesviridae. Once the virus infects a host cell, its double‑stranded DNA genome is delivered into the nucleus, where a coordinated cascade of immediate‑early, early, and late gene expression directs viral DNA replication, structural protein synthesis, and virion assembly. After primary infection of epithelial cells, HSV-1...