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Gastroesophageal Reflux Disease II: Clinical Features and Management01:29

Gastroesophageal Reflux Disease II: Clinical Features and Management

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Related Experiment Video

Updated: Jul 13, 2026

Simultaneous Laryngopharyngeal and Conventional Esophageal pH Monitoring
06:46

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Published on: December 14, 2020

Reflux symptom index versus reflux finding score.

Tamer A Mesallam1, Joseph C Stemple, Tarek M Sobeih

  • 1Blaine Block Institute for Voice Analysis and Rehabilitation, Dayton, Ohio, USA.

The Annals of Otology, Rhinology, and Laryngology
|August 4, 2007
PubMed
Summary

This study found a strong correlation between the Reflux Symptom Index (RSI) and the Reflux Finding Score (RFS) in patients with laryngopharyngeal reflux. Hoarseness and throat clearing were key symptoms linked to specific laryngeal findings.

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Area of Science:

  • Otolaryngology
  • Gastroenterology

Background:

  • Laryngopharyngeal reflux (LPR) presents with diverse laryngeal symptoms.
  • The Reflux Symptom Index (RSI) and Reflux Finding Score (RFS) are commonly used to assess LPR.
  • Understanding the correlation between symptom reporting and objective laryngeal findings is crucial for diagnosis and management.

Purpose of the Study:

  • To examine the correlation between the RSI and RFS.
  • To identify specific laryngeal signs and symptoms most significantly associated with LPR.

Main Methods:

  • Retrospective chart review of 40 randomly selected patients.
  • Videostroboscopic laryngeal examination with RFS rating by 6 experienced raters.
  • Assessment of interrater and intrarater reliability for RFS.
  • Statistical comparison of RSI and RFS total scores and individual parameters.

Main Results:

  • High interrater and intrarater reliability for RFS.
  • A significant positive correlation was found between total RSI and RFS scores (p < .0001).
  • Hoarseness strongly correlated with vocal fold edema and thick laryngeal mucus (p < .01).
  • Excessive throat clearing significantly correlated with thick endolaryngeal mucus (p < .01).

Conclusions:

  • The RSI and RFS are highly correlated, supporting their combined use in LPR assessment.
  • Specific symptoms like hoarseness and throat clearing are significantly linked to objective laryngeal findings in LPR.