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[Studies on chemical constitutes of Acantophora spicifera]
Da-yong Shi1, Li-jun Han, Jie Sun
1Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, China.
Objective:
To study the chemical constitutes of Acantophora spicifera.
Method:
Compounds were isolated by normal phase silica gel and Sephadex LH-20 gel column chromatography, and reverse-phase HPLC, as well as recrystallization. Their structures were elucidated by spectroscopic methods.
Result:
Seven compounds were isolated from A. spicifera and their structures were identified as aplysin (1), loloilide (2), (R)-(-)-dehydrovomifoliol (3), uracil (4), thymine (5), 1-methoxy-4-(1-propenyl) benzene (6).
Conclusion:
The compounds were obtained from this genus for the first time. Compound 6 was firstly obtained from marine organisms.
