[Acid-excretion function of the kidneys in hypothyroidism]

Impairment of renal acid excretion characterized by reduced excretion of titrated acids, ammonia and ammonia coefficient, occurs in clinically decompensated hypothyroidism. Disturbed urinary acidification accompanies severe hypothyroidism. Administration of thyroid hormones brings about normalization of titrated acids excretion, urinary acidification, ammoniogenesis undergoes positive changes. It is shown that capacity of the kidneys to maintain acid-base homeostasis under acid loading in hypothyroidism is limited.