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Related Experiment Videos

[The respiratory function in children with collagen disease].

N Wada1, K Fukunaga, T Obata

  • 1Department of Pediatrics, The Jikei University School of Medicine, Tokyo.

Ryumachi. [Rheumatism]
|October 1, 1991
PubMed
Summary

Many children with collagen diseases experience respiratory issues, with restrictive lung function being common in Systemic Lupus Erythematosus and Mixed Connective Tissue Disease. Monitoring respiratory function is crucial for managing these pediatric patients.

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Area of Science:

  • Pediatric Rheumatology
  • Pulmonary Medicine
  • Internal Medicine

Context:

  • Collagen diseases can affect multiple organ systems, including the respiratory system.
  • Pediatric patients with collagen diseases are at risk for pulmonary complications.
  • Limited data exists on the specific respiratory function abnormalities in children with various collagen diseases.

Purpose:

  • To investigate the prevalence and types of respiratory function abnormalities in children diagnosed with collagen diseases.
  • To identify specific collagen diseases associated with higher risks of respiratory impairment.
  • To highlight the importance of respiratory function monitoring in the clinical management of pediatric collagen disease.

Summary:

  • Respiratory function tests were conducted on 60 children with collagen diseases, revealing abnormalities in 45% of cases.

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  • Restrictive lung function abnormalities were most common (52%), followed by obstructive (22%) and mixed (26%) types.
  • Systemic Lupus Erythematosus (SLE) and Mixed Connective Tissue Disease (MCTD) showed a notable proportion of patients with restrictive respiratory changes.

    • Impact:

    • Findings underscore the significant impact of collagen diseases on pediatric respiratory health.
    • Highlights the need for routine pulmonary function assessments in children diagnosed with collagen-related disorders.
    • Provides valuable data for clinicians managing pediatric patients with collagen diseases, emphasizing proactive respiratory care.