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Related Concept Videos

Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Ophthalmic Drug Delivery Systems01:23

Ophthalmic Drug Delivery Systems

Ophthalmic drug delivery faces major limitations due to poor absorption across the corneal membrane. This process is primarily driven by diffusion and is influenced by two main factors: the physicochemical properties of the drug and tear drainage. Most ophthalmic drugs, such as pilocarpine, epinephrine, atropine, and local anesthetics, are weak bases. They are typically formulated at an acidic pH to enhance chemical stability. However, this leads to high ionization, reducing their ability to...
Local Anesthetics: Common Agents and Their Applications01:23

Local Anesthetics: Common Agents and Their Applications

Local anesthetics (LAs) are commonly used for various applications in medical and dental procedures. Some of the common agents used are cocaine, lidocaine, and bupivacaine.
Cocaine is an ester of benzoic acid and methylecgogine. It is used to anesthetize and vasoconstrict locally. Currently, it is used primarily for topical applications. It is beneficial for surgeries on the upper respiratory tract, providing anesthesia and shrinking the mucosa. Cocaine in the form of cocaine hydrochloride is...

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Related Experiment Video

Updated: Jul 13, 2026

Ultrasound Cyclo Plasty in Eyes with Glaucoma
05:05

Ultrasound Cyclo Plasty in Eyes with Glaucoma

Published on: January 26, 2018

[Self-medication with local anaesthetics by glaucoma patients using teletonometry].

G Schäffner1, S Antal, C Jürgens

  • 1Klinik und Poliklinik für Augenheilkunde, Universitätsklinikum Greifswald der Ernst-Moritz-Arndt-Universität, AöR, Greifswald.

Der Ophthalmologe : Zeitschrift Der Deutschen Ophthalmologischen Gesellschaft
|August 4, 2007
PubMed
Summary

Glaucoma patients can safely self-administer topical anesthetics for self-tonometry, with most experiencing only minor, temporary side effects. Regular ophthalmological check-ups are crucial for safe home use of these eye drops.

Related Experiment Videos

Last Updated: Jul 13, 2026

Ultrasound Cyclo Plasty in Eyes with Glaucoma
05:05

Ultrasound Cyclo Plasty in Eyes with Glaucoma

Published on: January 26, 2018

Area of Science:

  • Ophthalmology
  • Clinical Pharmacology

Background:

  • Self-tonometry is increasingly important for glaucoma management.
  • Home application of topical anesthetics is necessary for contact self-tonometry.
  • Concerns exist regarding the safety of patient self-medication with local anesthetics.

Purpose of the Study:

  • To evaluate the local tolerability of topical anesthetics used by glaucoma patients during self-tonometry.
  • To assess the safety and side effect profile of proparacaine eyedrops in a home-use setting.

Main Methods:

  • A prospective clinical study involving 100 glaucoma patients over 1 year.
  • Patients performed self-tonometry for at least 6 months using a modified tonometer.
  • Proparacaine-HCl 0.5% eyedrops were self-administered before each measurement, with tolerability assessed via a standardized questionnaire and visual analogue scales.

Main Results:

  • Data from 83 patients showed good tolerability; only two experienced allergic reactions requiring a change in anesthetic.
  • Most participants (91.5%) reported subjective symptoms of mild intensity.
  • Minor conjunctival hyperemia was the most frequent side effect, typically resolving within 1 hour.

Conclusions:

  • Self-medication with topical anesthetics for self-tonometry on undamaged ocular surfaces is generally safe for glaucoma patients.
  • The practice requires adherence to routine ophthalmological examinations and recommendations.
  • Integrating self-tonometry into modern glaucoma management requires comprehensive care concepts.