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[HPV-infection].

S Schmidt-Petruschkat1

  • 1Fachärztin f. Gynäkologie u. Geburtshilfe Dysplasiesprechstunde, Inst. für Zytologie und Genetik Nordrhein, Virchow-Str. 20, D-46047 Oberhausen. silke.schmidt-petruschkat@gmx.de

MMW Fortschritte Der Medizin
|August 7, 2007
PubMed
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Human papillomavirus (HPV) vaccines offer promising immunoprophylaxis against HPV-associated diseases. These vaccines can prevent cervical carcinoma, a leading cancer in women, and other anogenital dysplasias and warts.

Area of Science:

  • Oncology
  • Virology
  • Immunology

Context:

  • Cervical carcinoma is a significant global health concern, ranking as the third most common cancer in women worldwide.
  • Anogenital dysplasia and genital warts are prevalent conditions posing substantial healthcare challenges.
  • The incidence of cervical cancer is particularly high in certain regions, emphasizing the need for effective prevention strategies.

Purpose:

  • To highlight the advent and potential of prophylactic vaccines against Human Papillomavirus (HPV).
  • To underscore the role of HPV vaccination in preventing HPV-associated diseases, including cervical carcinoma.
  • To present immunoprophylaxis as a key strategy in managing HPV-related health issues.

Summary:

  • Bivalent and quadrivalent vaccines targeting specific HPV types (HPV 16, 18, 6, 11) have been developed.

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  • These vaccines provide a promising approach for immunoprophylaxis.
  • The vaccines aim to prevent the development of HPV-associated diseases, most notably cervical carcinoma.

    • Impact:

    • Vaccination has the potential to significantly reduce the global burden of cervical cancer.
    • Widespread HPV vaccination can decrease the incidence of anogenital dysplasia and genital warts.
    • This development represents a major advancement in preventive medicine for women's health.