Related Experiment Video
Updated: Jul 13, 2026
04:36
Implantation Protocol of the Foldable Capsular Vitreous Body for Complex Vitreoretinal Surgery
Published on: April 14, 2026
Postoperative complications associated with 25-gauge pars plana vitrectomy
Omesh P I Gupta1, Eric D Weichel, Carl D Regillo
1Retina Service, Wills Eye at Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Summary
Twenty-five-gauge pars plana vitrectomy (PPV) shows rare complications, with cataract progression and hypotony being most frequent. Fluid-filled eyes may have increased risks of wound leakage and hypotony post-PPV.
Area of Science:
- Ophthalmology
- Retinal Surgery
- Minimally Invasive Ophthalmic Procedures
Background:
- 25-gauge pars plana vitrectomy (PPV) is a minimally invasive surgical technique.
- Understanding postoperative complications is crucial for patient outcomes.
Purpose of the Study:
- To evaluate the incidence and types of intraoperative and postoperative complications following 25-gauge PPV.
- To compare complication rates in eyes filled with fluid, air, or gas.
Main Methods:
- Retrospective review of 70 consecutive eyes undergoing 25-gauge PPV.
- Data collected included visual acuity, intraocular pressure, and operative/postoperative complications.
- Minimum follow-up of 12 weeks was required.
Main Results:
- Mean visual acuity improved significantly post-PPV (20/368 to 20/105).
- Intraoperative complications: retinal tears (2.9%).
- Postoperative complications: cataract progression (42.5%), cystoid macular edema (7.1%), retinal detachment (1.4%), hypotony (5.7%).
- Fluid-filled eyes showed higher risk of wound leakage and hypotony compared to air or gas-filled eyes.
Conclusions:
- 25-gauge PPV is associated with a low rate of intraoperative and postoperative complications.
- Cataract progression and hypotony are the most common postoperative issues.
- Fluid infusion during 25-gauge PPV may increase the risk of hypotony and wound leakage.
Related Concept Videos
01:25Glaucoma: Overview
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
01:23Peripheral Artery Disease V: Postoperative Nursing Management
During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
01:25Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications
Peritoneal dialysis (PD) is a medical process that removes waste products and excess fluid from the body using the peritoneal membrane as a natural filter.Peritoneal Dialysis MethodsSeveral methods can be used for peritoneal dialysis, including Acute Intermittent Peritoneal Dialysis, Continuous Ambulatory Peritoneal Dialysis, and Automated Peritoneal Dialysis, also known as Continuous Cyclic Peritoneal Dialysis.Acute Intermittent Peritoneal Dialysis (AIPD) is used for patients with uremic...
01:28Angle Closure Glaucoma: Treatment
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
01:27Open Angle Glaucoma: Treatment
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...