Related Experiment Video
Updated: Jun 14, 2026

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
Published on: February 16, 2016
Stroke and ventricular dysfunction in a patient with isolated left ventricular noncompaction
Makoto Nakajima1, Teruyuki Hirano, Hideki Doi
1Department of Medicine, Kumamoto Rosai Hospital. nakazima@fc.kuh.kumamoto-u.ac.jp
Cardioembolic stroke in a patient with isolated noncompaction of the ventricular myocardium may indicate worsening heart function. Anticoagulation may be best initiated when left ventricular systolic function declines below normal levels.
Area of Science:
- Cardiology
- Neurology
Background:
- Isolated noncompaction of the ventricular myocardium is a rare cardiac condition.
- Cardioembolic stroke is a serious complication that can arise from cardiac abnormalities.
Observation:
- A 44-year-old woman presented with a cardioembolic stroke.
- Transthoracic echocardiography revealed isolated noncompaction of the ventricular myocardium.
- Left ventricular systolic function was initially mildly depressed and worsened significantly over three months.
Findings:
- The cardioembolic stroke likely occurred as left ventricular systolic function began to deteriorate.
- This case suggests a correlation between declining ventricular function and embolic events in noncompaction patients.
Implications:
- Early monitoring of left ventricular systolic function is crucial in patients with isolated noncompaction.
- Initiating anticoagulation when left ventricular systolic function falls below normal may prevent stroke in these patients.
Related Concept Videos
Imbalances in Cardiac Output
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send blood...
Mitral Stenosis I: Introduction
Cardiomyopathy II: Dilated Cardiomyopathy
Cardiomyopathy III: Hypertrophic Cardiomyopathy
Cardiomyopathy IV: Restrictive Cardiomyopathy
Cardiomyopathy V: Interprofessional Care

