Prevalence of recurrent wheezing in infants

Herberto J Chong Neto1, Nelson Augusto Rosário, Dirceu Solé

  • 1Universidade Federal do Paraná (UFPR), Curitiba, PR, Brazil. h.chong@uol.com.br

Jornal De Pediatria
|August 7, 2007
PubMed

Insights

Recurrent wheezing is common in infants in Curitiba, Brazil, affecting nearly half of those studied. Many infants experienced early-onset wheezing, suggesting a potential link to childhood asthma.

Area of Science:

  • Pediatric respiratory health
  • Epidemiology of infant wheezing

Background:

  • Recurrent wheezing in infants is a significant health concern.
  • Understanding its prevalence is crucial for early diagnosis and management.

Purpose of the Study:

  • To determine the prevalence of recurrent wheezing in infants in Curitiba, Brazil.
  • To analyze the onset, symptoms, and treatment of wheezing episodes in this population.

Main Methods:

  • A cross-sectional study involving 1,364 infants aged 12-15 months in Curitiba.
  • Standardized questionnaires administered to parents regarding wheezing, respiratory infections, and risk factors.
  • Data collected from health centers between August 2005 and December 2006.

Main Results:

  • 45.4% of infants experienced wheezing in their first year, with onset around 5.5 months.
  • 22.6% had three or more wheezing episodes.
  • Wheezing was associated with nocturnal symptoms, breathing difficulties, emergency visits, hospital admissions, and a medical diagnosis of asthma, particularly in those with frequent episodes.

Conclusions:

  • Infants in Curitiba exhibit a high prevalence of early-onset wheezing with significant morbidity.
  • Frequent wheezing episodes in infancy may indicate a higher likelihood of developing asthma.
  • Further investigation into the long-term outcomes and asthma development in this cohort is warranted.
Abstract

Related Concept Videos

Asthma I: Introduction01:28

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
Asthma-I: Introduction01:29

Asthma-I: Introduction

Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
Respiratory Syncytial Virus Disease01:29

Respiratory Syncytial Virus Disease

Human respiratory syncytial virus (RSV) is a widespread pathogen that primarily targets infants and young children but also poses a serious health risk to elderly and immunocompromised individuals. Belonging to the Pneumoviridae family, RSV is a negative-sense, single-stranded RNA virus within the Pneumovirus genus. Its global health burden is significant, with millions of cases annually resulting in hospitalizations and mortality, particularly in resource-limited settings. Although most...
Pulmonary Cycle: Exhalation01:17

Pulmonary Cycle: Exhalation

In terms of human respiration, the act of expelling air, known as exhalation (or expiration), operates on the principle of pressure gradients. During expiration, the pressure within the lungs exceeds that of the surrounding atmosphere. Under normal conditions, quiet breathing involves passive exhalation and is free of muscular contractions. This is because the exhalation process is driven by the natural elastic recoil of the lungs and chest wall, both of which have an inherent tendency to...
Asthma III: Clinical Manifestations01:13

Asthma III: Clinical Manifestations

Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...
Asthma-III: Symptoms and Complications01:24

Asthma-III: Symptoms and Complications

Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma