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Spatially addressable multiprotein nanoarrays templated by aptamer-tagged DNA nanoarchitectures

Rahul Chhabra1, Jaswinder Sharma, Yonggang Ke

  • 1Department of Chemistry and Biochemistry and The Biodesign Institute, Arizona State University, Tempe, Arizona 85287, USA.

Journal of the American Chemical Society
|August 7, 2007
PubMed
Abstract

No abstract available in PubMed .

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DNA Microarrays

Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...