Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Diversity in Cell Signaling Responses01:22

Diversity in Cell Signaling Responses

The physiological function of a cell and cellular communication are outcomes of a range of extrinsic signals, intracellular signaling pathways, and cellular responses. No two cell types express the same repertoire of signaling components. Receptors are highly selective for their cognate ligands, but once activated, they can alter multiple cellular processes such as DNA transcription, protein synthesis, and metabolic activity. 
Graded and Abrupt Responses
Some signaling systems generate...
Protein Diffusion in the Membrane01:24

Protein Diffusion in the Membrane

Proteins show rotational as well as lateral diffusion across the membrane. The lateral diffusion of proteins was confirmed through the cell fusion experiment where mouse and human cells were fused, resulting in hybrid cells. When the human and mouse cells fused, the specific membrane proteins on human and mouse cells were marked with the red and green-fluorescent markers, respectively. Initially, the red and green fluorescence was located on the respective hemisphere of the cell. As time...
Diffusion01:21

Diffusion

Diffusion is a type of passive transport. In passive transport, a substance tends to move from an area of high concentration to an area of low concentration until the concentration is equal across the space. For example, take the diffusion of substances through the air. When someone opens a perfume bottle in a room filled with people, the perfume is at its highest concentration in the bottle and is at its lowest at the edges of the room. The perfume vapor will diffuse, or spread away, from the...
Diffusion01:12

Diffusion

Diffusion is the passive movement of substances down their concentration gradients—requiring no expenditure of cellular energy. Substances, such as molecules or ions, diffuse from an area of high concentration to an area of low concentration in the cytosol or across membranes. Eventually, the concentration will even out, with the substance moving randomly but causing no net change in concentration. Such a state is called dynamic equilibrium, which is essential for maintaining overall...
Fast Reactions01:27

Fast Reactions

Fast reactions occurring in times shorter than the time needed to mix reactants pose a unique challenge for investigation. In a liquid-phase continuous-flow system, reactants A and B are swiftly pushed into the mixing chamber, where mixing occurs within 1 ms. The reaction mixture then flows through an observation tube, and one measures light absorption to determine species concentrations at various points of the tube. This method is most appropriate when relatively large volumes of reactants...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Decoding cellular population dynamics through mechanistic modelling and statistical data analysis.

NPJ systems biology and applications·2026
Same author

Optimal experiment design for practical parameter identifiability and model discrimination.

Mathematical biosciences·2026
Same author

3D epithelial cell topology tunes signaling range to promote precise patterning.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Problems, Progress and Perspectives in Mathematical and Computational Biology.

Bulletin of mathematical biology·2026
Same author

Networked collective dynamics in animal ecology and cell biology.

Physics of life reviews·2026
Same author

Growth rate-driven modelling suggests that phenotypic adaptation drives drug resistance in BRAFV600E-mutant melanoma.

Communications biology·2026

Related Experiment Video

Updated: Jul 13, 2026

Visualizing Zygotic Genome Activation In Single Cells of Early Embryos
07:30

Visualizing Zygotic Genome Activation In Single Cells of Early Embryos

Published on: April 3, 2026

Speed of reaction diffusion in embryogenesis.

Karen M Page1, Nicholas A M Monk, Philip K Maini

  • 1Department of Mathematics, University College London, Gower Street, London WC1E 6BT, United Kingdom. kpage@math.ucl.ac.uk

Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics
|August 7, 2007
PubMed
Summary

Reaction diffusion systems can form patterns quickly enough for embryonic development. This study explores the speed of pattern formation in reaction diffusion models, finding it applicable to morphogenesis.

More Related Videos

A Method of Permeabilization of Drosophila Embryos for Assays of Small Molecule Activity
10:04

A Method of Permeabilization of Drosophila Embryos for Assays of Small Molecule Activity

Published on: July 13, 2014

Fast and Efficient Expression of Multiple Proteins in Avian Embryos Using mRNA Electroporation
09:40

Fast and Efficient Expression of Multiple Proteins in Avian Embryos Using mRNA Electroporation

Published on: June 7, 2019

Related Experiment Videos

Last Updated: Jul 13, 2026

Visualizing Zygotic Genome Activation In Single Cells of Early Embryos
07:30

Visualizing Zygotic Genome Activation In Single Cells of Early Embryos

Published on: April 3, 2026

A Method of Permeabilization of Drosophila Embryos for Assays of Small Molecule Activity
10:04

A Method of Permeabilization of Drosophila Embryos for Assays of Small Molecule Activity

Published on: July 13, 2014

Fast and Efficient Expression of Multiple Proteins in Avian Embryos Using mRNA Electroporation
09:40

Fast and Efficient Expression of Multiple Proteins in Avian Embryos Using mRNA Electroporation

Published on: June 7, 2019

Area of Science:

  • Developmental biology
  • Mathematical biology
  • Biophysics

Background:

  • Reaction diffusion systems are proposed mechanisms for embryonic patterning.
  • Previous research focused on steady-state patterns and robustness, with less known about pattern formation timescales.
  • Single morphogen diffusion models show patterning occurs on realistic timescales for short distances.

Purpose of the Study:

  • To investigate the time scales of pattern formation in reaction diffusion systems.
  • To determine if reaction diffusion patterning is sufficiently fast for morphogenesis.

Main Methods:

  • Analysis of specific reaction diffusion models.
  • Exploration of pattern formation speed in these models.

Main Results:

  • Reaction diffusion has the potential for faster patterning than single morphogen diffusion.
  • The study addresses the speed of pattern formation in reaction diffusion systems.

Conclusions:

  • Patterning via reaction diffusion is potentially fast enough for morphogenesis.
  • Further investigation into the speed of reaction diffusion patterning is warranted.