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Persistent placoid maculopathy: a new clinical entity.

Pamela R Golchet1, Lee M Jampol, David Wilson

  • 1Department of Ophthalmology, Northwestern University, Chicago, Illinois 60611, USA.

Ophthalmology
|August 7, 2007
PubMed
Summary
This summary is machine-generated.

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A new eye condition, persistent placoid maculopathy, resembles serpiginous choroiditis but has a distinct clinical course. Most patients develop choroidal neovascularization, leading to vision loss.

Area of Science:

  • Ophthalmology
  • Medical Research
  • Clinical Case Studies

Background:

  • Macular serpiginous choroiditis is a rare inflammatory eye condition.
  • A distinct clinical entity with features mimicking serpiginous choroiditis has been observed.

Observation:

  • Six patients aged 50-68 presented with unique macular lesions.
  • Lesions were well-delineated, whitish, and placoid, involving the macula but sparing peripapillary areas.
  • Visual acuity remained good initially, even with foveal involvement, until complications arose.

Findings:

  • The condition, termed persistent placoid maculopathy, differs from serpiginous choroiditis in its clinical course and angiographic findings.
  • Choroidal neovascularization (CNV) occurred in 11 of 12 eyes, leading to disciform scars in 9.

Related Experiment Videos

  • Unlike serpiginous choroiditis, chorioretinal scarring was absent unless secondary to CNV.

    • Implications:

    • Persistent placoid maculopathy represents a novel clinical entity.
    • Early foveal involvement does not necessarily predict poor visual acuity in this condition.
    • The high incidence of CNV underscores the risk of central vision loss in affected individuals.