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Updated: Jul 13, 2026

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
12:45

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing

Published on: December 11, 2017

Surgical aspects of cardiac resynchronisation therapy

S M Shaw1, S G Williams, D J Fox

  • 1North West Regional Cardiac and Transplant Unit, University Hospital of South Manchester, NHS Hospitals Foundation Trust, Manchester, UK.

Scandinavian Journal of Surgery : SJS : Official Organ for the Finnish Surgical Society and the Scandinavian Surgical Society
|August 8, 2007
PubMed

Insights

Cardiac resynchronisation therapy (CRT) improves outcomes for heart failure patients with ventricular dyssynchrony. This review explores CRT concepts, comparing surgical versus transvenous left ventricular (LV) lead implantation.

Area of Science:

  • Cardiology
  • Medical Devices

Background:

  • Heart failure remains a significant cause of mortality and morbidity despite pharmacological advances.
  • Cardiac resynchronisation therapy (CRT) offers benefits for patients with ventricular dyssynchrony.
  • Existing studies show CRT improves mortality and reduces symptom burden.

Purpose of the Study:

  • To review key concepts of cardiac resynchronisation therapy (CRT).
  • To discuss the implications of surgical left ventricular (LV) lead implantation compared to the transvenous approach.

Main Methods:

  • Review of existing literature on CRT.
  • Comparative analysis of surgical and transvenous LV lead implantation techniques.

Main Results:

  • CRT has demonstrated significant benefits in improving mortality and reducing symptoms in selected heart failure patients.
  • Surgical LV lead implantation presents an alternative approach to the standard transvenous method, with distinct implications.

Conclusions:

  • CRT is a valuable addition to heart failure management for patients with ventricular dyssynchrony.
  • Understanding the nuances of LV lead implantation is crucial for optimizing CRT outcomes.

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