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Updated: Jul 13, 2026

Collecting Sleep, Circadian, Fatigue, and Performance Data in Complex Operational Environments
Published on: August 8, 2019
How early in treatment is PAP adherence established? Revisiting night-to-night variability
Mark S Aloia1, J Todd Arnedt, Michael Stanchina
1Department of Medicine, National Jewish Medical and Research Center, Room A109b, 1400 Jackson St.,Denver, CO 80206, USA. aloiam@njc.org
Abstract:
Obstructive sleep apnea (OSA) is a serious disorder with significant daytime consequences. Treatment for OSA most commonly takes the form of positive airway pressure (PAP). Although effective, PAP adherence is often below expectations. Previous studies have suggested that early PAP use can predict long-term adherence, but these studies have not been replicated, nor has follow up been longer than 3 months. This article presents a replication study enhanced by a longer follow up and additional data to suggest that 6-month adherence can be predicted within the first days of PAP use. This article also discusses how this might relate to the experience of significant side effects of treatment.
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