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Synchronous metastatic malignant melanoma and primary adenocarcinoma in the colon

Hsin-Hui Chiu1, Yao-Wen Liu, Chien-Chih Huang

  • 1Division of Gastroenterology, Department of Medicine and Pathology, Kuo General Hospital, Tainan, Taiwan.

Gastrointestinal Endoscopy
|August 8, 2007
PubMed
Abstract

No abstract available in PubMed .

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Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
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The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
Tumor Progression02:07

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Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
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