Effects of nutritional support long time after total gastrectomy

Area of Science:

• Gastroenterology
• Nutritional Science
• Surgical Oncology

Background:

• Long-term nutritional status after total gastrectomy remains poorly understood.
• The efficacy of individualized nutritional support requires further investigation.
• Current dietary counseling is often poorly defined.

Purpose of the Study:

• To evaluate the long-term effects of individualized oral nutritional support following total gastrectomy.
• To assess the impact of nutritional intervention on nutritional status and energy metabolism.

Main Methods:

• Individualized dietary advice focused on energy and protein-rich foods and supplements.
• Monthly counseling sessions were provided.
• Key metrics including body weight, food intake, body composition, and energy expenditure were monitored over 12 months.

Main Results:

• No significant changes in body weight, body composition, or energy metabolism were observed at 12 months post-intervention.
• Weight changes were heterogeneous among patients.
• Patients who remained healthy with a BMI < 25 experienced weight gain (p<0.05), unlike those with co-morbidities or higher initial BMI.

Conclusions:

• Oral nutritional intervention did not significantly alter long-term outcomes in patients post-total gastrectomy.
• Intercurrent co-morbidity significantly influences the effectiveness of nutritional support.
• Nutritional support demonstrated greater efficacy in healthy patients with a BMI < 25.