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Updated: Jul 13, 2026
08:12
Experimental Methods to Study Human Postural Control
Published on: September 11, 2019
[Simulation model of local mechanisms controlling the human systemic circulation vessels during postural tests]
Aviakosmicheskaia I Ekologicheskaia Meditsina = Aerospace and Environmental Medicine
|August 9, 2007
Summary
This study presents a nonpulsatile model of human systemic circulation to simulate posture changes. The model aids in understanding blood flow dynamics and myogenic regulation in different body segments.
Area of Science:
- Physiology
- Biomedical Engineering
- Computational Modeling
Context:
- Human systemic circulation is complex, with blood flow dynamics significantly affected by posture changes.
- Investigating peripheral circulation and myogenic regulation presents experimental challenges due to nonlinear distortions.
Purpose:
- To develop a nonpulsatile computational model of human systemic circulation.
- To simulate the effects of posture changes on blood flow indices in various vessels and body segments.
- To represent myogenic regulation of peripheral circulation.
Summary:
- The model integrates hemodynamics, hydrodynamic, hydrostatic circulation, and myogenic regulation components.
- It allows for the investigation of myogenic regulation in peripheral circulation across different vessels and body segments.
- Future work includes developing an algorithm for hemodynamic index computation during tilt and standing tests.
Impact:
- Provides a novel tool for studying cardiovascular responses to postural changes.
- Facilitates research into the complex interplay of hemodynamics and myogenic regulation.
- Enables more accurate simulation of physiological responses in clinical and research settings.
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