Related Experiment Videos
The association between serum leptin and blood lymphocytes in hemodialysis patients
1Hajar Medical, Educational and Therapeutic Center, Department of Internal Medicine, Shahrekord University of Medical Sciences, Shahrekord, Iran. hamidnasri@yahoo.com
Aims:
To find the association between serum leptin, blood lymphocytes and PMN percentages as markers of immune-system function, as well as nutritional status in long term hemodialysis patients.
Patients And Methods:
In a group of long term hemodialysis patients, serum leptin, albumin, creatinine, BUN, and white-blood cell (WBC) count--[lymphocytes and polymorphonuclear (PMN) cells] were measured.
Results:
A significant positive correlation between serum leptin and body-mass index and between serum leptin and lymphocyte percentage was found, as well as a significant negative correlation between serum leptin and PMN percentage. There was a weak negative correlation between WBC counts and the duration and dosage of dialysis, and also a near significant negative correlation between WBC counts and hemodialysis adequacy. There was also a significant negative correlation between WBC counts and serum albumin.
Conclusion:
Generally increased neutrophil coun and increased lymphocyte count markers of an increased mortality in hemodialysis patients. This study shows a positive association between serum leptin and lymphocytes, and a negative correlation between serum leptin and PMN. Leptin might have a protective role in decreasing mortality in hemodialysis patients by maintaining the function of the immune system (Tab. 1, Fig. 3, Ref 33).
Related Concept Videos
Nephrotic Syndrome II : Assessment and Medical Management
Nephrotic Syndrome I : Introduction
Serum Studies: Renal Function Tests
Blood Studies for Cardiovascular System III: Serum Lipid Profile
Serum lipids are fats and fatty substances in the blood and are crucial for various bodily functions, including energy storage, cellular structure, and hormone production. Serum lipids consist of cholesterol, triglycerides, and phospholipids.
Cholesterol is a soft, fat-like substance found in all body cells. It is crucial for producing hormones, vitamin D, and substances that aid...
Chronic Kidney Disease III: Interprofessional Care