Related Experiment Video
Updated: Jul 13, 2026

A Conflict Model of Reward-seeking Behavior in Male Rats
Published on: February 20, 2019
Five-factor model personality traits in opioid dependence
1Norwegian Knowledge Centre for the Health Services, Olavsplass, Oslo, Norway. hege.kornor@kunnskapssenteret.no
Opioid dependence is linked to distinct personality traits, including higher Neuroticism and lower Extraversion and Conscientiousness. These findings suggest personality differences between individuals with opioid use disorder and the general population.
Area of Science:
- Psychology
- Psychiatry
- Addiction Research
Background:
- Personality traits are implicated in the development of opioid dependence.
- The Five Factor Model (FFM) categorizes personality into Neuroticism, Extraversion, Openness to Experience, Agreeableness, and Conscientiousness.
- Limited research exists on specific personality patterns in opioid dependence.
Purpose of the Study:
- To investigate differences in FFM personality traits between individuals with opioid dependence and a non-clinical control group.
- To determine if a distinct personality profile is associated with opioid dependence.
Main Methods:
- Compared FFM personality traits in 65 opioid-dependent patients (in buprenorphine therapy) with an age- and sex-matched non-clinical sample.
- Utilized the Norwegian version of the Revised NEO Personality Inventory (NEO PI-R) for personality assessment.
- Calculated Cohen's d effect sizes to quantify differences in personality trait scores.
Main Results:
- Opioid-dependent individuals scored significantly higher on Neuroticism.
- Opioid-dependent individuals scored significantly lower on Extraversion and Conscientiousness (medium to large effect sizes).
- Small effect sizes were observed for Openness to Experience and Agreeableness.
Conclusions:
- Significant differences in personality traits exist between opioid-dependent individuals and their non-clinical peers.
- Neuroticism, Extraversion, and Conscientiousness appear to be key differentiating personality factors in opioid dependence.
- These findings support the role of specific personality traits in the aetiology and presentation of opioid dependence.
More Related Videos
09:54Combining Laser Capture Microdissection and Microfluidic qPCR to Analyze Transcriptional Profiles of Single Cells: A Systems Biology Approach to Opioid Dependence
Published on: March 8, 2020
09:29Investigating Drivers of Antireward in Addiction Behavior with Anatomically Specific Single-Cell Gene Expression Methods
Published on: August 4, 2022
Related Concept Videos
Five-Factor Theory of Personality
Openness reflects creativity, curiosity, and openness to new experiences. Individuals scoring high in openness are imaginative, have a wide range of interests, and are independent thinkers. Low...
Drug Abuse and Addiction: Pharmacological Phenomena
Opioid Receptors: Overview
Personality Disorders: Dependent and Obsessive-Compulsive
Dependent Personality Disorder
Dependent personality disorder is characterized by an excessive reliance on others to manage various aspects of life. Individuals with this disorder often struggle with...
Drug Dependence
Opioid Analgesics: Synthetic and Semisynthetic Opioids