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Updated: Jul 13, 2026

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Published on: December 9, 2015
[Adult onset Still's disease: review of 26 cases]
Elena Riera Alonso1, Alejandro Olivé Marqués, Meritxell Sallés Lizarzaburu
1Sección de Reumatología, Hospital Universitari Germans Trias i Pujol, Badalona, Barcelona, España.
Background And Objective:
We intended to describe the clinical characteristics, treatment and evolution of 26 patients with adult onset Still's disease.
Patients And Method:
This was a retrospective study (1984-2004). The clinical records of patients with adult onset Still's disease were reviewed.
Results:
Twenty six patients were included. Most frequent clinical characteristics were: fever (100%), arthritis (81%), rash (92%) sore throat (92%) and lymphadenopathy (42%). Aspirin controlled the disease in 27% of patients, prednisone was needed in 70% and methotrexate was added in 50% cases. A monocyclic course was seen in 54% and polycyclic in 46% patients.
Conclusions:
The clinical characteristics were similar to previous series. A febrile polyarthritis was the most frequent presentation form. A polycyclic course was found in 58% of cases and it seems to be associated with poor prognosis and need for aggressive treatment.
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