Related Experiment Video
Updated: Jul 13, 2026

Skin Biopsy for Diagnosing Discoid Lupus Erythematosus
Published on: June 10, 2025
Toward a biopsychosocial approach to skin diseases
Angelo Picardi1, Paolo Pasquini
1Italian National Institute of Health, Centre of Epidemiology, Surveillance and Health Promotion, Rome, Italy.
Abstract:
A link between the mind and the skin has long been hypothesized. Indeed, some studies suggested that psychosocial factors may play a role in the pathogenesis and course of several skin diseases. Conversely, other studies suggested that psychiatric disorders and psychosocial difficulties may result as a complication of a primary skin disease. Epidemiological studies indeed found a high prevalence of psychiatric disorders among dermatological patients. This is a source of concern, because psychiatric morbidity is associated with emotional suffering, disability, lower quality of life, poorer adherence to dermatological treatment, and increased risk of self-harm. Conditions such as demoralization, health anxiety, irritable mood, type A behavior, and alexithymia were also found to be frequent in dermatological patients, and to be independently associated with greater psychological distress, lower quality of life, and poorer psychosocial functioning. Several studies also raised concerns about under-recognition and undertreatment of psychiatric disorders. This large body of findings suggests that psychosocial issues deserve more attention in everyday dermatological practice, and highlights the need for a biopsychosocial approach to the management of patients with skin disease. To this purpose, the development of efficient consultation-liaison services enabling an effective collaboration between dermatologists and mental health professionals is mandatory.
Related Concept Videos
Skin Diseases and Disorders
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Theoretical Approaches to Psychological Disorder
Biological approach
The biological approach posits that internal, organic factors are the primary causes of such disorders. This perspective emphasizes brain structure and function, genetic predispositions, and neurotransmitter imbalances. For example, schizophrenia has been associated with both genetic...
Changes in Skin Color: Clinical Perspectives
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Skin Cancer
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
The Skin Microbiota
Introduction to the Integumentary System
The skin, which is the primary organ of the integumentary system, consists of three main layers: the epidermis, dermis, and hypodermis (subcutaneous tissue). The epidermis is the...