Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Hemodiafiltration with endogenous reinfusion.

Mary Lou Wratten1, Paolo M Ghezzi

  • 1Research Scientist, Sorin Group Italia, Mirandola, Italy.

Contributions to Nephrology
|August 9, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Vitamins (A, C and E) and oxidative status of hemodialysis patients treated with HFR and HFR-Supra.

BMC nephrology·2016
Same author

Copeptin and high sensitive troponin for a rapid rule out of acute myocardial infarction?

Clinical laboratory·2011
Same author

Effects of acetate-free haemodiafiltration (HDF) with endogenous reinfusion (HFR) on cardiac troponin levels.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association·2010
Same author

Coupled plasma filtration adsorption.

Contributions to nephrology·2007
Same author

Effect of haemodiafiltration with online regeneration of ultrafiltrate on oxidative stress in dialysis patients.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association·2007
Same author

Disinfection of dialysis monitors.

Contributions to nephrology·2006

Hemofiltrate reinfusion (HFR) offers a sterile, online method for producing dialysis fluid, reducing physiological losses and inflammation. This technique enhances hemodiafiltration (HDF) for patients with complex conditions.

Area of Science:

  • Nephrology
  • Biomedical Engineering
  • Clinical Medicine

Background:

  • Hemodiafiltration (HDF) improves solute clearance but traditionally requires large volumes of sterile reinfusion fluid.
  • Early HDF methods using individual fluid bags presented challenges in handling, cost, and contamination risk.
  • Technological advancements have focused on online sterile fluid production for HDF.

Purpose of the Study:

  • To introduce and evaluate Hemofiltrate Reinfusion (HFR) as an online method for producing sterile reinfusion fluid.
  • To assess the clinical benefits of HFR in reducing physiological component loss and associated patient stress.
  • To highlight the biocompatibility and ease of use of the HFR technique.

Main Methods:

  • Utilizing a 2-chamber filter system to regenerate patient ultrafiltrate into sterile reinfusion fluid.

Related Experiment Videos

  • Employing a sorbent bed within a closed circuit to purify and regenerate the fluid.
  • Reinfusing physiologically important substances like bicarbonates and amino acids.

    • Main Results:

    • HFR successfully produces sterile and apyrogenic reinfusion fluid online.
    • The technique minimizes the loss of essential physiological components during HDF.
    • Clinical studies show HFR is associated with reduced inflammation and oxidative stress.
    • HFR demonstrates ease of use and high biocompatibility.

    Conclusions:

    • Hemofiltrate reinfusion (HFR) provides a safe and efficient online method for preparing sterile dialysis fluid.
    • HFR mitigates the loss of vital substances and reduces inflammation and oxidative stress in patients undergoing HDF.
    • This technique is particularly beneficial for patients with complex risk factors like malnutrition, inflammation, and atherosclerosis.