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Clinical aspects of haemodiafiltration

Francesco Locatelli1, Salvatore Di Filippo

  • 1Department of Nephrology and Dialysis, A. Manzoni Hospital, Lecco, Italy.

Contributions to Nephrology
|August 9, 2007
PubMed

Standard haemodialysis is not a very efficacious treatment of chronic uraemia and patient mortality rate is still very high. The 2002 results of the HEMO study showed that alternative treatments such as 'high-efficiency haemodialysis' and 'high-flux haemodialysis' are associated with a non-significant reduction in the relative risk of mortality (4 and 8%, respectively). In an attempt to define the clinical impact of haemodiafiltration, we review some of the efficacy data from clinical studies in light of a number of factors that may be related to the high mortality among haemodialysis patients.

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