Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Bipolar Disorder

Bipolar Disorder

Bipolar disorder is a chronic mental health condition marked by significant mood fluctuations, including episodes of mania and depression. Elevated energy levels, heightened mood or irritability, impulsive behavior, reduced sleep needs, rapid speech, racing thoughts, inflated self-esteem, and distractibility characterize mania. Individuals with bipolar disorder often alternate between depressive and manic states, with periods of emotional stability lasting an average of six months to a year.

Mania and Antimanic Drugs: Overview

Mania and Antimanic Drugs: Overview

Mania, a psychological condition characterized by elevated mood, increased energy, and reduced sleep need, is part of the bipolar disorder cycle. The exact cause of mania isn't entirely known, but it is thought to be a combination of genetic, environmental, and neurological factors. Bipolar disorder involves alternating manic and depressive episodes. Mood stabilizers like lithium, antipsychotics, and anticonvulsants help manage these episodes. Lithium carbonate is particularly effective as a...

Negative and Cognitive Symptoms of Schizophrenia

Negative and Cognitive Symptoms of Schizophrenia

Negative symptoms of schizophrenia indicate a reduction or absence of typical behaviors and emotional responses found in healthy individuals, while positive symptoms reflect an excess or distortion of normal functioning.
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...

Depressive Disorders: MDD and Dysthymia

Depressive Disorders: MDD and Dysthymia

Depressive disorders are a group of mental health conditions characterized by pervasive feelings of sadness, diminished pleasure in life, and a significant impact on daily functioning. These conditions are most prevalent in individuals during their 30s and affect women at twice the rate of men. Contrary to popular belief, younger individuals are generally more susceptible to these disorders than older adults. Two key types of depressive disorders include Major Depressive Disorder (MDD) and...

Depression: Overview

Depression: Overview

Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...

Depressive Disorders: Etiology

Depressive Disorders: Etiology

Depressive disorders result from a complex interplay of biological, psychological, and sociocultural factors, each contributing uniquely to the development and persistence of the condition. Understanding these factors provides critical insight into the multifaceted nature of depression.
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Do Autistic Traits Predict Obsessive-Compulsive Symptoms? A Community-Based Study.

Psychological reports·2025

Same author

Emerging Roles of Non-coding RNAs on Symptom Type and Cognitive Functions in Schizophrenia and Schizoaffective Disorder.

Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology·2025

Same author

COVID-19 Vaccine Hesitancy and Its Relationship With Illness Risk Perceptions, Affect, Worry, and Public Trust: An Online Serial Cross-Sectional Survey From Turkey.

Psychiatry and clinical psychopharmacology·2024

Same author

Association Between Mood Disorder Severity, Treatment Response and Systemic Inflammatory Markers: Exploring the Role of NLR, PLR, MLR, and SII.

Psychiatry and clinical psychopharmacology·2024

Same author

An Evaluation of Psychogenic Predictors of Non-Organic Erectile Dysfunction.

Medicina (Kaunas, Lithuania)·2023

Same author

Cognitive outcomes of transcranial magnetic stimulation in treatment-resistant depression: a randomized controlled study.

Turkish journal of medical sciences·2023

Search research articles

Related Experiment Video

Updated: Jul 13, 2026

Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder

Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder

Published on: April 26, 2024

Cognitive functions in euthymic patients with bipolar disorder.

Osman Ozdel¹, Filiz Karadag, Figen C Atesci

¹Department of Psychiatry, Faculty of Medicine, Pamukkale University, Denizli, Turkey. osmanlal@yahoo.com

Annals of Saudi Medicine

|August 9, 2007

Summary

Bipolar disorder patients exhibit persistent cognitive deficits in attention and memory, even during euthymia. These impairments correlate with illness severity, indicating potential trait abnormalities.

Related Experiment Videos

Last Updated: Jul 13, 2026

Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder

Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder

Published on: April 26, 2024

Area of Science:

Neuroscience
Psychiatry
Cognitive Psychology

Background:

Cognitive dysfunction is a significant concern in bipolar disorder.
Understanding cognitive performance during euthymia is crucial for treatment.

Purpose of the Study:

To compare cognitive performance in euthymic bipolar patients versus healthy controls.
To identify specific cognitive domains affected in bipolar disorder.

Main Methods:

Evaluated 27 euthymic bipolar patients and 21 healthy controls.
Assessed verbal/visual memory, attention, executive, and psychosocial functions.

Main Results:

Bipolar patients demonstrated deficits in attention, executive functions, and memory.
Illness duration and episode history correlated with poorer cognitive performance.
Psychosocial functioning was not linked to cognitive deficits.

Conclusions:

Euthymic bipolar patients show persistent deficits in inhibitory control, selective attention, and memory.
Cognitive impairment is associated with illness duration and episode history.
Attentional dysfunction may represent a trait abnormality in bipolar disorder.