Related Experiment Video
Updated: Jul 13, 2026
Real-Time Cardiac Mapping with a Noninvasive Imageless Electrocardiographic Imaging System
Published on: April 11, 2025
Catheter based simultaneous mapping of cardiac activation and motion: a review
Hanno U Klemm1, Olaf Franzen, Rodolfo Ventura
1Department of Cardiology, University Heart Center Hamburg, Martinistrasse 52, 20246 Hamburg Germany. h.klemm@uke.uni-hamburg.de
Insights
Assessing heart failure requires understanding both electrical and mechanical heart function. New mapping systems, like NOGA-XP, enable combined analysis for improved diagnosis and treatment strategies.
Area of Science:
- Cardiology
- Biomedical Engineering
- Medical Imaging
Background:
- Heart failure presents a growing challenge, necessitating deeper understanding of myocardial electrical and mechanical function.
- Current cardiac function assessment relies heavily on imaging techniques evaluating cardiac motion.
- Biventricular resynchronization therapy highlights the growing importance of electrical properties in heart failure management.
Purpose of the Study:
- To review the principles of percutaneous catheter-based assessment of cardiac electrical activation and mechanical motion.
- To discuss experimental setups and findings related to combined electromechanical mapping.
- To explore the potential of novel mapping systems for analyzing cardiac function.
Main Methods:
- Review of fundamental principles for catheter-based activation and motion assessment.
- Presentation of experimental setups for electromechanical mapping.
- Discussion of findings from systems like the NOGA-XP.
Main Results:
- QRS widening is not a reliable surrogate for asynchronous contraction in heart failure.
- Electromechanical mapping systems, such as NOGA-XP, are capable of combined electrical and mechanical function analysis.
- Temporal analysis of motion propagation represents a novel aspect in electromechanical mapping.
Conclusions:
- Combined analysis of electrical and mechanical function is crucial for understanding heart failure.
- Percutaneous catheter-based mapping systems offer promising avenues for advanced cardiac assessment.
- Further research into temporal motion propagation analysis can enhance diagnostic capabilities for heart failure.
Abstract:
Heart failure as a result of a variety of cardiac diseases is an ever growing, challenging condition that demands profound insight in the electrical and mechanical state of the myocardium. Assessment of cardiac function has largely relied on evaluation of cardiac motion by multiple imaging techniques. In recent years electrical properties have gained attention as heart failure could be improved by biventricular resynchronization therapy. In contrast to early belief, QRS widening as a result of left bundle branch block could not be identified as a surrogate for asynchronous contraction. The combined analysis of electrical and mechanical function is yet a largely experimental approach. Several mapping system are principally capable for this analysis, the most prominent being the NOGA-XP system. Electromechanical maps have concentrated on the local shortening of the reconstructed endocardial surface from end-diastole to end-systole. Temporal analysis of motion propagation, however, is a new aspect. The fundamental principles of percutaneous catheter based activation and motion assessment are reviewed. Related experimental setups are presented and their main findings discussed.
More Related Videos
Related Concept Videos
01:28Imaging Studies for Cardiovascular System V: CT
01:24Cardiac Catheterization III: Left Heart Catheterization