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Prevalence of sub-clinical vitamin A deficiency in 2-5-year-old children in Tehran
N Rostami1, A R Farsar, N Shiva
1Department of Paediatrics, Taleghani Hospital. rostaminahid@yahoo.com
Insights
Sub-clinical vitamin A deficiency affects 23.6% of children aged 2-5 in Tehran, indicating a public health concern. This condition, identified via conjunctival impression cytology (CIC), was linked to child
Area of Science:
- Nutritional Science
- Ophthalmology
- Public Health
Background:
- Vitamin A deficiency is a significant global health issue, particularly in children.
- Conjunctival impression cytology (CIC) is a method for assessing vitamin A status.
- Understanding vitamin A status in urban and rural populations is crucial for targeted interventions.
Purpose of the Study:
- To ascertain the prevalence of vitamin A deficiency in children aged 2-5 years in Tehran using CIC.
- To identify demographic and socioeconomic factors associated with vitamin A deficiency in this population.
Main Methods:
- A cross-sectional study involving 1257 children aged 2-5 years in Tehran.
- Data collection included conjunctival impression cytology (CIC) for vitamin A status assessment.
- Information on supplemental vitamin A intake, recent infections, and socioeconomic factors was recorded.
Main Results:
- Sub-clinical vitamin A deficiency, indicated by abnormal CIC, was detected in 23.6% of the children.
- This prevalence classifies the deficiency as a moderate public health problem in the studied population.
- Abnormal CIC showed a statistically significant association with the child's sex and age.
Conclusions:
- A significant proportion of children aged 2-5 years in Tehran exhibit sub-clinical vitamin A deficiency.
- The findings highlight the need for public health strategies to address vitamin A insufficiency in this age group.
- Sex and age are identified as potential risk factors influencing vitamin A status in children.
Abstract:
To determine vitamin A status using conjunctival impression cytology (CIC) in children aged 2-5 years, we assessed 1257 randomly selected children in urban and rural areas of Tehran. History of using supplemental vitamin A, respiratory or diarrhoeal infection in the previous 6 months, residential location, parents' education, family economic status, and child's age, sex and weight were recorded. Sub-clinical vitamin A deficiency (defined as abnormal CIC) was found in 23.6% of the sample, a rate classified as a moderate public health problem. There was a statistically significant relationship between sex and age and abnormal CIC (P < 0.05).
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