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Published on: October 20, 2022
Juvenile idiopathic oligoarthritis: analysis of 42 cases in Jordan
A M Al-Wahadneh1, A F Abu-Zeid, W H Khreisat
1Paediatric Immunology Clinic, Department of Paediatrics, King Hussein Medical Centre, Royal Medical Services, Amman, Jordan. awah88@hotmail.com
Insights
Juvenile idiopathic oligoarthritis often presents as monoarthritis, primarily affecting the knee in young children. Many patients experienced delayed diagnosis due to extensive initial work-ups.
Area of Science:
- Pediatric Rheumatology
- Immunology
Background:
- Juvenile idiopathic oligoarthritis (JIO) is a chronic autoimmune condition affecting children.
- Early diagnosis and management are crucial for optimal outcomes in JIO.
Purpose of the Study:
- To describe the clinical characteristics of JIO patients.
- To evaluate the diagnostic process and identify potential delays in management.
Main Methods:
- Retrospective chart review of 42 JIO patients diagnosed between 1995 and 2004.
- Analysis of patient demographics, clinical presentation, joint involvement, and associated conditions like uveitis and antinuclear antibodies (ANAs).
Main Results:
- The study included 42 patients (9 males, 33 females) aged 1.2-15.2 years.
- Most patients (64%) presented with monoarthritis, commonly affecting the knee (71%).
- Asymptomatic uveitis occurred in 21% of patients, particularly those under 3 years and with positive ANAs.
Conclusions:
- JIO in this cohort was characterized by monoarthritis, often involving the knee.
- A significant proportion of patients experienced delayed diagnosis, necessitating a review of diagnostic pathways.
Abstract:
We conducted a retrospective chart review for all 42 patients, 9 males and 33 females, diagnosed with juvenile idiopathic oligoarthritis between July 1995 and October 2004 at the paediatric rheumatology clinic in King Hussein Medical Centre. Age range was 1.2-15.2 years, mean 3.6 (standard deviation 2.4) years. Of those <6 years, 80% were females. Most patients (64%) had monoarthritis; the knee was the most common joint affected (71%). Two patients had developed extended oligoarthritis. Nine (21%) had asymptomatic uveitis: 6 females (P = 0.350), 7 (77%) <3 years of age (P = 0.301) and 7 (77%) with antinuclear antibodies (ANAs) (P = 0.071). Eighteen (43%) females were positive for ANAs. Most patients had undergone unnecessary, lengthy work-up and treatment before diagnosis.
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