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Updated: Jul 13, 2026

An Efficient Sieving Method to Isolate Intact Glomeruli from Adult Rat Kidney
Published on: November 1, 2018
[Specific features of a course of chronic glomerulonephritis with onset in childhood]
Aim:
Analysis of the course and rate of progression of morphologically confirmed forms of chronic glonerulonephritis (CGN) with onset in childhood and adolescence (1950 to 2005).
Material And Methods:
The course of the disease was examined in 110 patients with morphologically verified form of CGN with onset in childhood. Maximal history of CGN was 42 years.
Results:
CGN was morphologically mesangio-proliferative in 50.9% patients, while nephritis with minimal alterations occurred only in 10% patients. Most of the patients (71; 64.6%) had secondary hypertension, chronic renal failure (39; 35.5%). Programmed hemodialysis was conducted in 14 (12.7%) patients, 10 (9.1%) patients died. Stable dysability developed in 41 (37.3%) patients. The most severe course of the diseases was observed in patients with family history of CGN.
Conclusion:
Recently, CGN with debut in childhood shows a trend to an unfavourable course, had severe manifestations at a disease debut, and progresses rapidly.
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