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[Intestinal damage by non-steroidal anti-inflammatory drugs].

José Luis Rocha Ramírez1, Javier Walter Parrado Montaño, Moisés Rojas Illanes

  • 1Servicio de Cirugía de Colon y Recto, Hospital de Especialidades CMN Siglo XXI IMSS, Av. Cuauhtémoc No. 330, Col. Doctores, C.P. 06700, México, DF. rochajlrr@hotmail.com

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Summary

Chronic use of Nonsteroidal anti-inflammatory Drugs (NSAIDs) can cause serious intestinal damage. Patients experiencing symptoms like diarrhea or bleeding should be evaluated for NSAID-induced enteropathy.

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Published on: February 27, 2014

Area of Science:

  • Gastroenterology
  • Internal Medicine
  • Pharmacology

Background:

  • Nonsteroidal anti-inflammatory Drugs (NSAIDs) are globally prevalent medications.
  • Gastrointestinal complications are a significant concern with NSAID use.

Observation:

  • Two clinical cases of intestinal damage linked to chronic NSAID ingestion are presented.
  • One case involved inflammatory bowel disease and jejunum enteropathy.
  • The second case featured digestive hemorrhage and right colon ulcers.

Findings:

  • Chronic NSAID use is associated with diverse forms of intestinal injury.
  • Symptoms such as diarrhea, bleeding, malnutrition, or anemia warrant investigation for NSAID-induced enteropathy.

Implications:

  • Clinicians should consider NSAID-induced intestinal damage in patients with relevant symptoms.
  • Early diagnosis and management are crucial for patients with NSAID-related gastrointestinal complications.