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Related Experiment Video

Updated: Jul 13, 2026

Characterizing Salmonella Typhimurium-induced Septic Peritonitis in Mice

Characterizing Salmonella Typhimurium-induced Septic Peritonitis in Mice

Published on: July 29, 2022

Multiorgan involvement due to Salmonella typhi: case report.

J E Ollé-Goig¹

¹St Francis Hospital, Buluba, Uganda, Catalan Association for the Control of Tuberculosis in the Third World (ACTMON), Barcelona, Spain.

East African Medical Journal

|August 10, 2007

Summary

A 12-year-old boy with osteomyelitis developed severe Salmonella typhi infection, including endocarditis. Prompt treatment with ceftriaxone and ciprofloxacin led to a full recovery, highlighting effective antimicrobial strategies for severe typhoid fever.

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Published on: August 11, 2014

Area of Science:

Pediatrics
Infectious Diseases
Microbiology

Background:

Typhoid fever, caused by Salmonella Typhi, is a systemic infection.
Complications can include osteomyelitis, endocarditis, and pericarditis, particularly in pediatric cases.

Observation:

A 12-year-old male presented with initial symptoms of osteomyelitis and poliarthritis.
During hospitalization, the patient developed severe complications: subcutaneous abscesses, endocarditis, and pericarditis.

Findings:

Blood cultures confirmed the diagnosis of typhoid fever due to Salmonella Typhi.
The patient's severe presentation involved multiple organ systems.

Implications:

This case underscores the importance of considering typhoid fever in pediatric patients with severe systemic infections and unusual presentations.
Successful treatment with ceftriaxone and ciprofloxacin demonstrates the efficacy of these antibiotics in managing complicated typhoid fever.
Early diagnosis and appropriate antimicrobial therapy are crucial for preventing life-threatening complications of typhoid fever.