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A challenge for regenerative medicine: proper genetic programming, not cellular mimicry

Angie Rizzino1

  • 1Eppley Institute for Research in Cancer and Allied Diseases, Department of Pathology and Microbiology, University of Nebraska Medical Center, Nebraska Medical Center, Omaha, Nebraska 68198-6805, USA. arizzino@unmc.edu

Developmental Dynamics : an Official Publication of the American Association of Anatomists
|August 10, 2007
PubMed
Summary

Cellular mimicry, not true cell reprogramming, may explain many stem cell plasticity findings. Identifying these look-alike cells using gene expression and epigenetic profiles is crucial for advancing regenerative medicine.

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