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Published on: June 2, 2015
MDCT of acute thrombotic and nonthrombotic pulmonary emboli
Sanjeev Bhalla1, Ignacio Lopez-Costa
1Division of Cardiothoracic Imaging, Mallinckrodt Institute of Radiology, 510 South Kingshighway Blvd., St. Louis, MO 63110, USA. bhallas@mir.wustl.edu
Abstract:
Acute pulmonary embolism (PE) remains a common clinical challenge. MDCT pulmonary angiography has become the first line imaging study in the diagnosis of PE because of its speed, accuracy, low-interobserver variability, and ability to provide alternative diagnoses. This review article highlights the role of MDCT in the evaluation of acute thrombotic PE in the era of PIOPED 2. MDCT findings of acute PE and some potential pitfalls are covered as well as some of the controversies in imaging young and pregnant patients. MDCT findings of acute non-thrombotic PE are also covered. This latter group may be occult on the angiographic portion of the study but may declare themselves through secondary findings. Their findings and potential mimics are included so that the interpreting radiologist can make the most of a CT to rule out PE.
Insights
Acute pulmonary embolism (PE) is a common challenge. Multidetector CT (MDCT) pulmonary angiography is the primary diagnostic tool, offering speed and accuracy in detecting PE and alternative conditions.
Area of Science:
- Radiology
- Cardiovascular Imaging
- Pulmonary Medicine
Background:
- Acute pulmonary embolism (PE) presents a significant clinical challenge.
- Multidetector CT (MDCT) pulmonary angiography is the established first-line imaging modality for PE diagnosis.
- Its speed, accuracy, and ability to identify alternative diagnoses make it indispensable.
Purpose of the Study:
- To review the utility of MDCT in diagnosing acute thrombotic PE.
- To discuss MDCT findings, potential pitfalls, and controversies in specific patient populations (young, pregnant).
- To cover MDCT findings in acute non-thrombotic PE and their secondary indicators.
Main Methods:
- Review of current literature and guidelines concerning MDCT for PE diagnosis.
- Analysis of MDCT imaging findings in acute thrombotic and non-thrombotic PE.
- Discussion of diagnostic challenges and alternative diagnoses.
Main Results:
- MDCT pulmonary angiography is highly accurate for diagnosing acute PE.
- Secondary findings on MDCT can reveal non-thrombotic causes of PE.
- Awareness of pitfalls and mimics is crucial for accurate interpretation.
Conclusions:
- MDCT is pivotal in the modern evaluation of acute PE.
- The review emphasizes maximizing CT utility for comprehensive PE assessment.
- Understanding both primary and secondary findings improves diagnostic yield and patient care.
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