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Updated: Jul 13, 2026

Identification of Protein Interaction Partners in Mammalian Cells Using SILAC-immunoprecipitation Quantitative Proteomics
Published on: July 6, 2014
The minimum information required for reporting a molecular interaction experiment (MIMIx)
Sandra Orchard1, Lukasz Salwinski, Samuel Kerrien
1European Molecular Biology Laboratory (EMBL) - European Bioinformatics Institute, Wellcome Trust Genome Campus, Cambridge, UK. orchard@ebi.ac.uk
Abstract:
A wealth of molecular interaction data is available in the literature, ranging from large-scale datasets to a single interaction confirmed by several different techniques. These data are all too often reported either as free text or in tables of variable format, and are often missing key pieces of information essential for a full understanding of the experiment. Here we propose MIMIx, the minimum information required for reporting a molecular interaction experiment. Adherence to these reporting guidelines will result in publications of increased clarity and usefulness to the scientific community and will support the rapid, systematic capture of molecular interaction data in public databases, thereby improving access to valuable interaction data.
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