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[Headache and migraine].

H C Diener1, M A Slomke, V Limmroth

  • 1Universitätsklinik für Neurologie, Universitätsklinikum, Hufelandstrasse 55, 45147, Essen, Germany. h.diener@uni-essen.de

Der Nervenarzt
|August 10, 2007
PubMed
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Headache knowledge has advanced significantly, with breakthroughs like triptans for migraines and new preventive therapies. However, chronic tension headache treatment remains challenging, and medication overuse headaches are a growing concern.

Area of Science:

  • Neurology
  • Clinical Medicine
  • Epidemiology

Background:

  • Headaches are highly prevalent disorders encountered frequently in medical practice.
  • Significant advancements in understanding headache epidemiology, pathophysiology, and treatment have occurred over the last century.

Purpose of the Study:

  • To review the progress in headache knowledge and treatment over the past 100 years.
  • To highlight current therapeutic options and unmet needs in headache management.

Main Methods:

  • Literature review of epidemiological, pathophysiological, and therapeutic studies on headaches.
  • Analysis of treatment advancements, including acute and preventive therapies for various headache types.

Main Results:

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  • Triptans represent a major breakthrough for acute migraine treatment.
  • Effective preventive therapies for migraines include beta-blockers, calcium antagonists, and neuromodulators.
  • Chronic tension headache treatment remains suboptimal.
  • Medication overuse headache is an emerging clinical issue.
  • Integrated care models show promise for managing chronic headache disorders.

    • Conclusions:

    • While significant progress has been made, particularly in migraine treatment, challenges remain for other headache types like chronic tension headache.
    • The increasing prevalence of medication overuse headache necessitates focused attention.
    • New care structures like integrated headache care offer improved patient support.