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The molecular basis of positional information
D Summerbell1, J C Smith, M Maden
1Limb Development Group, National Institute for Medical Research, Mill Hill, London.
In Vivo (Athens, Greece)
|September 1, 1991
Abstract:
Embryologists have dreamed of their own particular philosophers stone for 100 years. During that time they have repeatedly demonstrated the likely existence of signalling molecules or morphogens that control the pattern of development in the embryo. Now at last seems possible that some of these morphogens may have been identified. We review current evidence for the molecular basis of positional information.