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Updated: Jul 13, 2026

Echocardiographic Assessment Using Subxiphoid-Only Examination for Hypotensive Patients
Published on: April 18, 2025
Should routine echocardiography be performed in all patients with stroke?
Thomas Wolber1, Micha Maeder, Ramin Atefy
1Cardiovascular Center, Cardiology, University Hospital Zurich, Zurich, Switzerland. thomas.wolber@usz.ch <thomas.wolber@usz.ch>
Insights
Echocardiography effectively identifies cardiac sources of embolism in younger stroke patients. Routine screening is less beneficial for older individuals, where selective testing is recommended.
Area of Science:
- Neurology
- Cardiology
- Diagnostic Imaging
Background:
- Cardiogenic embolism is a significant cause of ischemic stroke, ranging from 15% to 30%.
- Echocardiography is commonly used to screen for cardiac embolism sources in stroke patients.
- The routine utility of echocardiography for this purpose is debated.
Purpose of the Study:
- To evaluate the diagnostic yield of echocardiography in unselected patients with acute ischemic stroke.
- To determine the effectiveness of echocardiography in identifying cardiac sources of embolism (CSE).
Main Methods:
- Consecutive patients with ischemic stroke or transient ischemic attack were enrolled.
- All patients underwent transthoracic echocardiography.
- Transesophageal echocardiography was used for selected patients.
Main Results:
- A potential cardiac source of embolism (CSE) was identified in 18% of 775 patients.
- Atrial fibrillation (7%) and patent foramen ovale (6%) were the most common CSEs.
- Diagnostic yield was higher in patients under 50, with a 10-fold lower number needed to test compared to patients over 70.
Conclusions:
- Echocardiography provides valuable information for determining ischemic stroke causes.
- Routine echocardiographic screening is not universally indicated for all stroke patients.
- Echocardiography is recommended for routine use in patients under 50 with stroke; selective use is advised for older patients.
Background:
Cardiogenic embolism accounts for 15% to 30% of ischemic strokes. Echocardiography is frequently being used as a screening test for sources of cardiac embolism in patients with stroke. However, the value of routine use of echocardiography for this task remains controversial. We evaluated the diagnostic yield of echocardiography in unselected patients with acute ischemic stroke.
Methods:
Consecutive patients with ischemic stroke or a transient ischemic attack were included in the study. Transthoracic echocardiography was performed in all patients, complemented by transesophageal echocardiography in selected patients.
Results:
In all, 807 echocardiographic examinations (743 transthoracic and 64 transesophageal) were performed in 775 consecutive patients. A potential cardiac source of embolism (CSE) was found in 144 (18%) of the patients. The most frequent potential causes of cardiac embolism included atrial fibrillation (7%) and patent foramen ovale (6%). Results were more likely to have impact on therapeutic decisions in younger patients. Numbers needed to test for detection of CSE increased 10-fold from 6 in patients younger than 50 years to 62 in patients aged 70 years and older.
Conclusion:
Echocardiography may provide important information on the cause of ischemic stroke. However, echocardiographic screening for a CSE is not warranted in all patients. In patients with younger than 50 years with stroke, echocardiography has a higher diagnostic yield and should routinely be performed. In older patients routine echocardiography results in a high rate of unspecific findings, and should be applied selectively, targeted at specific clinical questions.
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