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Updated: Jul 13, 2026

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques
Published on: June 11, 2019
Myocardial infarction with huge mural thrombus due to spontaneous coronary artery dissection detected by
Insights
A young man experienced chest discomfort and ECG abnormalities due to spontaneous coronary artery dissection (SCAD). Advanced imaging accurately diagnosed SCAD with left ventricular thrombus, avoiding myocardial infarction.
Area of Science:
- Cardiology
- Radiology
- Vascular Medicine
Background:
- A 28-year-old male presented with unexplained ECG abnormalities and chest discomfort.
- Initial evaluation was prompted by symptoms suggestive of cardiac compromise in a patient with no prior cardiovascular history.
Observation:
- Echocardiogram revealed regional wall motion abnormalities, left ventricular aneurysm, and a large mural thrombus.
- Coronary angiography identified a dissection in the mid-left anterior descending (LAD) coronary artery.
- ECG-gated 64-multidetector computed tomography (MDCT) confirmed the LAD dissection.
Findings:
- The case highlights spontaneous coronary artery dissection (SCAD) as a cause of cardiac symptoms in young adults.
- A significant finding was the presence of a large left ventricular mural thrombus associated with SCAD.
- Crucially, despite the dissection and thrombus, there was no evidence of acute myocardial infarction.
Implications:
- MDCT provides an accurate, non-invasive method for diagnosing SCAD and associated complications.
- This case underscores the importance of considering SCAD in young individuals presenting with cardiac symptoms.
- Early and accurate diagnosis is critical for managing SCAD and preventing adverse cardiac events like myocardial infarction.
Abstract:
A 28-year-old man without medical history of cardiovascular disease came to the clinic to have the cause of his ECG abnormalities and chest discomfort evaluated. Echocardiogram showed regional wall motion abnormality of the anteroseptum and inferoseptum from the upper mid-left ventricle to apex with aneurysm and anterior wall from the mid-left ventricle to apex. It also showed huge and broad mural thrombus (5.2x1.4 cm in size) harboring in the left ventricle. Coronary angiography revealed a middle part of left anterior descending coronary artery (LAD) dissection with good distal flow. ECG gated 64-multidetector computed tomography (MDCT) demonstrated the proximal and middle part of LAD dissection. There has been no observation of myocardial infarction with huge mural thrombi complicating a spontaneous coronary artery dissection in which MDCT allowed an accurate and non-invasive diagnosis.
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