Related Experiment Video
Updated: Jul 13, 2026

Myocardial Infarction by Percutaneous Embolization Coil Deployment in a Swine Model
Published on: November 4, 2021
Coronary artery embolisation
Insights
A large blood clot (embolus) was observed moving in the coronary artery during treatment for acute inferior myocardial infarction. This complication of percutaneous coronary intervention can lead to poor outcomes if not managed with appropriate medication.
Area of Science:
- Interventional Cardiology
- Cardiovascular Medicine
- Medical Imaging
Background:
- Percutaneous coronary interventions (PCI) are standard treatments for acute myocardial infarction.
- Coronary artery embolization is a recognized complication of PCI, potentially causing myocardial damage.
- Effective pharmacological therapy is crucial for managing PCI-related complications.
Observation:
- During primary stent implantation for acute inferior myocardial infarction, a macroscopic embolus was visualized.
- The embolus was observed moving within the right coronary artery.
- This event occurred after the initial diagnostic catheter contrast injection.
Findings:
- Unexpected macroscopic embolization can occur even with diagnostic procedures.
- The presence of an embolus poses a risk of reduced treatment efficacy and adverse outcomes.
- Inadequate upstream pharmacological therapy can exacerbate the negative consequences of coronary embolization.
Implications:
- Highlights the importance of vigilance for embolization during PCI, even in early stages.
- Underscores the need for optimized pre-procedural and intra-procedural pharmacological strategies.
- Suggests potential benefits of dedicated embolic protection devices in specific scenarios.
Abstract:
In the setting of an acute inferior myocardial infarction undergoing primary stent implantation, we could document a macroscopic embolus moving along the right coronary artery. Coronary embolisation is a well known drawback of percutaneous coronary interventions and dedicated devices can be used in order to minimize myocardial damage. Nonetheless, unexpected macroscopic embolisation after the first manual contrast injection through a diagnostic catheter remains a possible complication and may lead to unsatisfactory results when the upstream pharmacological therapy is not appropriate.
Related Concept Videos
Coronary Artery Disease V: Interprofessional Care
Acute Coronary Syndrome IV: Interprofessional Care
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
Peripheral Artery Disease III: Interprofessional Care
Acute Coronary Syndrome I: Introduction
Angina IV: Management

