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[Lipoprotein profiles in 6-year-old children breast fed for different periods of time]
M Hromadová1, M Skultétyová, A Randusková
1Ustav experimentálnej endokrinológie, Slovenská akadémia vied, Bratislava.
Insights
Breastfeeding for three months in infancy offered the most favorable lipoprotein profile and lowest atherosclerosis risk in six-year-old children. This longitudinal study highlights early nutrition
Area of Science:
- Pediatric Nutrition and Cardiovascular Health
- Lipid Metabolism and Atherosclerosis Risk Factors
Context:
- Continuation of a longitudinal study on healthy children's nutrition.
- Previous findings indicated breastfeeding benefits cholesterol distribution.
Purpose:
- To investigate the long-term impact of infant feeding (breastfeeding duration) on lipoprotein profiles at age six.
- To assess atherosclerosis risk based on lipid and apolipoprotein levels.
Summary:
- Children breastfed for three months exhibited the most favorable lipoprotein profile and lowest atherosclerosis risk indexes at age six.
- No significant differences were observed in overall serum cholesterol, apolipoprotein A1, or apolipoprotein B levels across feeding groups.
Impact:
- Suggests a specific breastfeeding duration (three months) may be optimal for early cardiovascular health markers.
- Provides evidence for the lasting effects of infant nutrition on lipid profiles and atherosclerosis risk.
Abstract:
The authors submit results of investigations of the lipoprotein profile in six-year-old children fed a different diet during infancy. It is the continuation of previous results of a long-term longitudinal investigation of this group of healthy children which revealed a favourable effect of breastfeeding on the cholesterol distribution in lipoprotein fractions. Throughout the investigation the children were divided into four groups according to the breastfeeding period. At the age of six serum cholesterol was assessed and cholesterol in lipoprotein fractions, levels of apolipoproteins A1 and B and risk for the genesis and development of atherosclerosis were calculated. The most favourable lipoprotein profile was found in the group of children, breastfed for three months and with this corresponded also the lowest values of the risk indexes. The serum cholesterol concentration, levels of serum apolipoproteins A1 and B in different groups of children did not differ significantly.