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Updated: Jul 13, 2026

Identifying Dysregulated Genes Induced by Kaposi's Sarcoma-associated Herpesvirus (KSHV)
Published on: September 14, 2010
[Update on Kaposi's sarcoma]
J J Morand1, E Lightburn, F Simon
1Service de dermatologie Médecin, HIA Laveran, Marseille, France. MorandJJ@aol.com
Abstract:
Kaposi's sarcoma (KS) is a mesenchymal tumor involving blood and lymphatic vessels and induced by viral growth factors (HHV8-IL6). This article reviews the epidemiology, pathogenesis, clinical spectrum (classic KS, iatrogenic immunosuppressive KS, endemic African KS, and AIDS-KS), histological features, staging criteria and treatment of KS. Unlike industrialized countries that have benefited from widespread use of highly active antiretroviral therapy (HAART), developing countries continue to have a high incidence of AIDS-KS. Future therapeutic targets for KS are enhancement of immune function and treatment with angiogenesis inhibitors
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