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Updated: Jul 13, 2026

Multimodality Diagnosis of Mesenteric Ischemia
Published on: July 21, 2023
[Tonsillar hypertrophy and mesenteric adenopathies as the main manifestations in a patient with Whipple's disease]
Angel Cosme Jiménez1, Evelia Ojeda Pérez, Fernando Neira
1Servicio de Aparato Digestivo. Hospital Donostia. San Sebastián. Guipúzcoa. España. acosme@chdo.osakidetza.net.
Abstract:
Whipple's disease is an infrequent chronic infection caused by Tropheryma whipplei, identified in 1992. Intestinal, articular, central nervous system and cardiac involvement is common. The presence of abdominal adenopathies, especially mesenteric adenopathies, without peripheral adenopathies or gastrointestinal, articular, neurological or cardiac symptoms is rare. We present the case of a male patient with tonsillar hypertrophy, mesenteric adenopathies, fever and constitutional syndrome, leading to suspicion of lymphoma. Biopsy findings of the lingual tonsil and mesenteric adenopathies were compatible with Whipple's disease. The diagnosis was confirmed by blood polymerase chain reaction.
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