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Updated: Jul 13, 2026

Reduced Complications after Arterial Reconnection in a Rat Model of Orthotopic Liver Transplantation
Published on: November 7, 2020
Alcohol- and substance-dependent subjects: the correlated factors in qualifying for liver transplantation
L Gallimberti1, G Forza, P Angeli
1Toxicological Clinic of Addictions, General Hospital, University of Padua, Padua, Italy. luigi.gallimberti@unipd.it
Objectives:
To identify the most significant variables in determining if candidates with past or current addictions can be considered for liver transplantation.
Methods:
Data relating to 58 cases from January 2001 to December 2003 were collected and analyzed.
Results:
The decisional algorithm identified by discriminant analysis is based on the following variables: the duration of remission, treatment adherence, and the presence of a valid help relationship. Candidates undergoing initial remission (up to 12 months) must demonstrate both adherence and affective support; those with over 5 years of remission, however, are considered sufficiently reliable. A positive judgment is significantly correlated to overall survival and clinical improvement even without transplantation.
Conclusions:
In toxicological evaluation, treatment adherence and the presence of a valid help relationship for patients in remission from addictions can improve the selection criteria for liver transplantation, making it more dependable.
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