Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Kidney Transplant I: Introduction

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...

Tissue Transplantation

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...

Kidney Transplant III: Nursing Management

Kidney Transplant III: Nursing Management

Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...

Kidney Transplant II: Surgical Procedure

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...

Bone Marrow Sampling and Transplants

Bone Marrow Sampling and Transplants

Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

What is the role of physical exercise after surgery for gastric cancer? A scoping review.

ESMO gastrointestinal oncology·2026

Same author

Challenges for Midwives' Healthcare Practice in the Next Decade: COVID-19 - Global Climate Changes - Aging and Pregnancy - Gestational Alcohol Abuse.

La Clinica terapeutica·2020

Same author

Is the Arabin Pessary really useful in preventing preterm birth? A review of literature.

Journal of gynecology obstetrics and human reproduction·2020

Same author

A challenging diagnosis of reversible "vascular" dementia: Cerebral amyloid angiopathy-related inflammation.

Journal of neuroimmunology·2019

Same author

High prevalence of autoimmune diseases in women with endometriosis: a case-control study.

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology·2019

Same author

Surgical Technique Notes of Arterial Vascular Reconstruction During Kidney Transplantation: Personal Experience and Literature Review.

Transplantation proceedings·2019

Search research articles

Related Experiment Video

Updated: Jul 13, 2026

Co-transplantation of Human Ovarian Tissue with Engineered Endothelial Cells: A Cell-based Strategy Combining Accelerated Perfusion with Direct Paracrine Delivery

Co-transplantation of Human Ovarian Tissue with Engineered Endothelial Cells: A Cell-based Strategy Combining Accelerated Perfusion with Direct Paracrine Delivery

Published on: May 16, 2018

Fertility following solid organ transplantation.

M Framarino Dei Malatesta¹, M Rossi, B Rocca

¹Department of Gynecological Sciences and Perinatology, Paride Stefanini University of Rome La Sapienza School of Medicine, Rome, Italy. framarino@infinito.it

Transplantation Proceedings

|August 19, 2007

Summary

Pregnancy after solid organ transplantation is possible, but carries risks like hypertension. Careful management of immunosuppression is key for successful outcomes in transplant recipients.

More Related Videos

Z-Scores for Assessing Ovarian Reserve in Young Patients Undergoing Fertility Preservation

Z-Scores for Assessing Ovarian Reserve in Young Patients Undergoing Fertility Preservation

Published on: October 25, 2024

Orthotopic Rat Kidney Transplantation: A Novel and Simplified Surgical Approach

Orthotopic Rat Kidney Transplantation: A Novel and Simplified Surgical Approach

Published on: May 7, 2019

Related Experiment Videos

Last Updated: Jul 13, 2026

Co-transplantation of Human Ovarian Tissue with Engineered Endothelial Cells: A Cell-based Strategy Combining Accelerated Perfusion with Direct Paracrine Delivery

Co-transplantation of Human Ovarian Tissue with Engineered Endothelial Cells: A Cell-based Strategy Combining Accelerated Perfusion with Direct Paracrine Delivery

Published on: May 16, 2018

Z-Scores for Assessing Ovarian Reserve in Young Patients Undergoing Fertility Preservation

Z-Scores for Assessing Ovarian Reserve in Young Patients Undergoing Fertility Preservation

Published on: October 25, 2024

Orthotopic Rat Kidney Transplantation: A Novel and Simplified Surgical Approach

Orthotopic Rat Kidney Transplantation: A Novel and Simplified Surgical Approach

Published on: May 7, 2019

Area of Science:

Transplantation immunology
Reproductive medicine
Nephrology
Hepatology

Background:

Solid organ transplantation restores fertility in women, enabling successful pregnancies.
However, transplant recipients face increased risks of pregnancy complications, including hypertension and preeclampsia.

Purpose of the Study:

To evaluate pregnancy outcomes and complications in solid organ transplant recipients.
To assess the impact of pregnancy on transplant rejection rates.
To determine the safety of immunosuppressive therapy during pregnancy.

Main Methods:

Retrospective analysis of 70 pregnancies post-kidney transplant and 9 post-liver transplant.
Monitoring of immunosuppressive drug levels and pregnancy complications.
Assessment of transplant rejection rates and offspring development.

Main Results:

Hypertension was the most common complication (23% in kidney recipients, 1/9 in liver recipients).
One case of transplant rejection occurred in a patient who refused immunosuppression.
No significant increase in malformation rates was observed; one infant had hip dislocation.

Conclusions:

Pregnancy is feasible after solid organ transplantation, with careful immunosuppression management.
Hypertension is a frequent complication, necessitating close monitoring.
Long-term follow-up of children is crucial to assess developmental, immunological, and oncological outcomes.