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Related Concept Videos

Margin of Error01:27

Margin of Error

The margin of error is also called the maximum error of an estimate. The margin of error is the maximum possible or expected difference between the observed sample parameter value and the actual population parameter value. For proportion, it is the maximum difference between the value of sample proportion obtained from the data and the true value of population proportion. As the true value of the population parameter is not known, the margin of error is calculated using the sample statistic.
Self-Discrepancy and Its Effects01:29

Self-Discrepancy and Its Effects

Self-discrepancy theory explains how people compare their actual self to their ideal and ought selves and how mismatches between these self-guides can lead to emotional distress. Developed by E. Tory Higgins, the theory distinguishes among three components of self-concept: the actual self, the ideal self, and the ought self. These refer respectively to how individuals perceive themselves, how they aspire to be, and how they believe they are obligated to be. Emotional well-being, self-esteem,...
Self-Discrepancy Theory02:45

Self-Discrepancy Theory

One influential perspective on what motivates people's behavior is detailed in Tory Higgin's self-discrepancy theory (Higgins, 1987). He proposed that people hold disagreeing internal representations of themselves that lead to different emotional states.
Crossing over01:34

Crossing over

Unlike mitosis, meiosis aims for genetic diversity in its creation of haploid gametes. Dividing germ cells first begin this process in prophase I, where each chromosome—replicated in S phase—is now composed of two sister chromatids (identical copies) joined centrally.
The homologous pairs of sister chromosomes—one from the maternal and one from the paternal genome—then begin to align alongside each other lengthwise, matching corresponding DNA positions in a process called synapsis.
In order to...
Crossing Over01:30

Crossing Over

Crossing over is the exchange of genetic information between homologous chromosomes during prophase I of meiosis I. Genetic recombination gives rise to allelic diversity in the newly formed daughter cells. In humans, crossing over produces genetically distinct haploid egg and sperm cells that undergo fertilization to produce unique offspring. Before cell division starts, the germ cell’s chromosome(s) undergo duplication in the S phase of the cell cycle. As the cells enter prophase I, duplicated...
Crossing Over01:34

Crossing Over

Unlike mitosis, meiosis aims for genetic diversity in its creation of haploid gametes. Dividing germ cells first begin this process in prophase I, where each chromosome—replicated in S phase—is now composed of two sister chromatids (identical copies) joined centrally.
The homologous pairs of sister chromosomes—one from the maternal and one from the paternal genome—then begin to align alongside each other lengthwise, matching corresponding DNA positions in a process called synapsis.
In order to...

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Corrigendum to "Second round statewide sentinel-based population survey for estimation of the burden of active infection and anti-SARS-CoV-2 IgG antibodies in the general population of Karnataka, India, during January-February 2021" [IJID Regions Vol 1(2021) pages 107-116].

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Correction: Contact tracing of COVID-19 in Karnataka, India: Superspreading and determinants of infectiousness and symptomatic infection.

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Contact tracing of COVID-19 in Karnataka, India: Superspreading and determinants of infectiousness and symptomatic infection.

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Lessons from the mismanagement of the COVID-19 pandemic: A blueprint to reform CDC.

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Related Experiment Video

Updated: Jul 13, 2026

Visualization of Intensity Levels to Reduce the Gap Between Self-Reported and Directly Measured Physical Activity
05:59

Visualization of Intensity Levels to Reduce the Gap Between Self-Reported and Directly Measured Physical Activity

Published on: March 7, 2019

Mind the gap.

Jawaid Akhtar1, Bradford D Johnston, Edward P Krenzelok

  • 1Pittsburgh Poison Center, Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, USA.

The Journal of Emergency Medicine
|August 19, 2007
PubMed
Summary

The oxygen saturation gap, a difference between blood gas and pulse oximeter readings, can indicate abnormal hemoglobin. Awareness of this gap aids in diagnosing conditions like carbon monoxide poisoning.

Area of Science:

  • Medical Diagnostics
  • Clinical Chemistry

Background:

  • The oxygen saturation gap is defined as the discrepancy between calculated oxygen saturation from arterial blood gas analysis and pulse oximetry readings.
  • A gap exceeding 5% suggests potential abnormalities in hemoglobin, necessitating further investigation.

Observation:

  • This case report highlights a clinical scenario where the oxygen saturation gap was a critical diagnostic clue.
  • The patient presented with an abnormal saturation gap, prompting a deeper evaluation.

Findings:

  • The observed oxygen saturation gap was instrumental in identifying underlying hemoglobin abnormalities.
  • The diagnostic process confirmed carbon monoxide poisoning as the cause of the abnormal gap.

Implications:

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  • Recognizing and measuring the oxygen saturation gap can improve the early diagnosis of specific poisoning and hemoglobin disorders.
  • This emphasizes the clinical utility of the oxygen saturation gap in routine patient assessment and toxicological evaluations.